ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical effect of acupoint stimulating control (ASC) in treating obsessive compulsive neurosis.</p><p><b>METHODS</b>The comparative study was conducted in 65 patients with obsessive compulsive neurosis, they were divided into two groups, the 33 patients in the control group treated with chlorimipramine and the 32 in the tested group treated with ASC. The therapeutic efficacy and adverse reaction were assessed according to the standard for clinical efficacy evaluation by Yale-Brown scale for obsession (Y-BOCS)and adverse reaction scale.</p><p><b>RESULTS</b>The curative rate and markedly effective rate in the control group was 24.2% (8/33) and 27.3% (19/33), which in the tested group was 37.5% (12/32) and 34.4% (11/32) respectively. Significant difference was shown in comparison of Y-BOCS score between the two groups from the end of the 4th week of treatment (P < 0.05), indicating the efficacy in the tested group was better than that in the control group. Moreover, the occurrence of adverse reaction was higher in the control group than that in the tested group.</p><p><b>CONCLUSION</b>ASC is a treatment with good effect, less adverse reaction and favourable safety superior to the treatment by chlorimipramine.</p>